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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1974 1
1978 1
1986 2
1987 2
1988 1
1990 1
1991 1
1992 1
1997 1
1998 4
2000 1
2001 2
2002 3
2003 3
2004 2
2005 2
2006 2
2007 6
2008 3
2009 6
2010 3
2011 4
2012 5
2013 4
2014 3
2015 7
2016 6
2017 5
2018 4
2019 8
2020 5
2021 8
2022 7
2023 9
2024 2

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113 results

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Page 1
Engineered CAR-Macrophages as Adoptive Immunotherapies for Solid Tumors.
Sloas C, Gill S, Klichinsky M. Sloas C, et al. Front Immunol. 2021 Nov 24;12:783305. doi: 10.3389/fimmu.2021.783305. eCollection 2021. Front Immunol. 2021. PMID: 34899748 Free PMC article. Review.
A prominent example of this approach is the use of T cells engineered to express chimeric antigen receptors (CARs), which have demonstrated significant efficacy against some hematologic malignancies. Despite increasingly sophisticated strategies to harness immune cell func …
A prominent example of this approach is the use of T cells engineered to express chimeric antigen receptors (CARs), which have demonstrated …
Caspases control antiviral innate immunity.
Chen H, Ning X, Jiang Z. Chen H, et al. Cell Mol Immunol. 2017 Sep;14(9):736-747. doi: 10.1038/cmi.2017.44. Epub 2017 Jul 10. Cell Mol Immunol. 2017. PMID: 28690332 Free PMC article. Review.
Beyond their established roles in programmed cell death and inflammatory response, some caspases are also fundamental players in antiviral immunity by fine-tuning the levels of antiviral signaling adapters and cytokines, such as type I interferons, which serves as a major, sop …
Beyond their established roles in programmed cell death and inflammatory response, some caspases are also fundamental players in antiviral i …
miR-206/133b Cluster: A Weapon against Lung Cancer?
Pan JY, Sun CC, Bi ZY, Chen ZL, Li SJ, Li QQ, Wang YX, Bi YY, Li DJ. Pan JY, et al. Mol Ther Nucleic Acids. 2017 Sep 15;8:442-449. doi: 10.1016/j.omtn.2017.06.002. Epub 2017 Jun 7. Mol Ther Nucleic Acids. 2017. PMID: 28918043 Free PMC article. Review.
The miR-206/133b cluster has been verified to be dysregulated and plays a crucial role in lung cancer. miR-206 and miR-133b participate in lung tumor cell apoptosis, proliferation, migration, invasion, angiogenesis, drug resistance, and cancer treatment. The mechanisms are sop …
The miR-206/133b cluster has been verified to be dysregulated and plays a crucial role in lung cancer. miR-206 and miR-133b participate in l …
Pathogenesis mechanisms of phytopathogen effectors.
Sun L, Wu X, Diao J, Zhang J. Sun L, et al. WIREs Mech Dis. 2023 Mar;15(2):e1592. doi: 10.1002/wsbm.1592. Epub 2023 Jan 2. WIREs Mech Dis. 2023. PMID: 36593734 Review.
Plants commonly face the threat of invasion by a wide variety of pathogens and have developed sophisticated immune mechanisms to defend against infectious diseases. ...Different cell structures and unique cellular organelles carried by plant cells endow plant-specific defe …
Plants commonly face the threat of invasion by a wide variety of pathogens and have developed sophisticated immune mechanisms to defe …
Bioterrorism.
Kortepeter MG, Cieslak TJ, Eitzen EM. Kortepeter MG, et al. J Environ Health. 2001 Jan-Feb;63(6):21-4. J Environ Health. 2001. PMID: 11381472 Review.
Although biological agents have been used in warfare for centuries, several events in the past decade have raised concerns that they could be used for terrorism. Revelations about the sophisticated biological-weapons programs of the former Soviet Union and Iraq have …
Although biological agents have been used in warfare for centuries, several events in the past decade have raised concerns that they could b …
Regulation of Host-Pathogen Interactions via the Ubiquitin System.
Mukherjee R, Dikic I. Mukherjee R, et al. Annu Rev Microbiol. 2022 Sep 8;76:211-233. doi: 10.1146/annurev-micro-041020-025803. Annu Rev Microbiol. 2022. PMID: 36075095 Review.
Ubiquitination is a posttranslational modification that regulates a multitude of cellular functions. Pathogens, such as bacteria and viruses, have evolved sophisticated mechanisms that evade or counteract ubiquitin-dependent host responses, or even exploit the ubiquitin sy …
Ubiquitination is a posttranslational modification that regulates a multitude of cellular functions. Pathogens, such as bacteria and viruses …
Trauma-toxicology: concepts, causes, complications.
Barth H, Worek F, Steinritz D, Papatheodorou P, Huber-Lang M. Barth H, et al. Naunyn Schmiedebergs Arch Pharmacol. 2024 May;397(5):2935-2948. doi: 10.1007/s00210-023-02845-3. Epub 2023 Nov 24. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 37999755 Free PMC article. Review.
Examples for the first scenario is the release of toxic gases, chemicals, and particles during house fires, and for the second scenario, the use of chemical or biological weapons in the context of terroristic activities. Toxic substances can cause or enhance severe, life-t …
Examples for the first scenario is the release of toxic gases, chemicals, and particles during house fires, and for the second scenario, the …
Slaying SARS-CoV-2 One (Single-domain) Antibody at a Time.
Czajka TF, Vance DJ, Mantis NJ. Czajka TF, et al. Trends Microbiol. 2021 Mar;29(3):195-203. doi: 10.1016/j.tim.2020.12.006. Epub 2020 Dec 16. Trends Microbiol. 2021. PMID: 33446406 Free PMC article. Review.
Camelid-derived and synthetic single-domain antibodies (sdAbs) are emerging as potent weapons against the novel coronavirus, SARS-CoV-2. sdAbs are small, compact, thermostable immunoglobulin elements capable of binding targets with subnanomolar affinities. ...Once in hand, …
Camelid-derived and synthetic single-domain antibodies (sdAbs) are emerging as potent weapons against the novel coronavirus, SARS-CoV …
Nano/micromotors for security/defense applications. A review.
Singh VV, Wang J. Singh VV, et al. Nanoscale. 2015 Dec 14;7(46):19377-89. doi: 10.1039/c5nr06254c. Nanoscale. 2015. PMID: 26554557 Review.
These nanomotors will thus empower sensing and destruction where stirring large quantities of decontaminating reagents and controlled mechanical agitation are impossible or undesired. New technological breakthroughs and greater sophistication of micro/nanoscale machines wi …
These nanomotors will thus empower sensing and destruction where stirring large quantities of decontaminating reagents and controlled mechan …
Multiple enzymatic activities of a Sir2-HerA system cooperate for anti-phage defense.
Tang D, Chen Y, Chen H, Jia T, Chen Q, Yu Y. Tang D, et al. Mol Cell. 2023 Dec 21;83(24):4600-4613.e6. doi: 10.1016/j.molcel.2023.11.010. Epub 2023 Dec 13. Mol Cell. 2023. PMID: 38096825
Unexpectedly, this complex exhibits various enzymatic activities, including ATPase, NADase, helicase, and nuclease, which work together in a sophisticated manner to fulfill the antiphage function. Therefore, we name this defense system "Nezha" after a divine warrior in Chi …
Unexpectedly, this complex exhibits various enzymatic activities, including ATPase, NADase, helicase, and nuclease, which work together in a …
113 results